Description

(S)-4-Bromo-Homo-Ibotenic Acid CAS NO 121313-15-3 is a high-purity, chiral derivative of the potent neuroactive amino acid ibotenic acid, distinguished by its specific stereochemistry and bromine substitution. This compound serves as a critical pharmacological research tool and a valuable intermediate in the synthesis of advanced bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and academic research institutions focused on neuroscience, receptor studies, and medicinal chemistry.

Application

• Neuroscience Research: Acts as a selective ligand and tool compound for studying glutamate receptors (mGluRs) and ionotropic receptors in the central nervous system.
• Medicinal Chemistry Intermediate: Serves as a key chiral building block for the synthesis of novel neuropharmaceuticals and receptor modulators.
• Biochemical Assay Development: Used in the development and validation of high-throughput screening assays for drug discovery programs targeting neurological pathways.
• Pharmacological Reference Standard: Employed as a certified reference material (CRM) for analytical method development and quality control in research laboratories.
• Academic & Institutional Research: Fundamental research into excitatory amino acid function, neurotoxicity, and synaptic transmission mechanisms.

Basic Information

Product Name	(S)-4-Bromo-Homo-Ibotenic Acid
CAS No.	121313-15-3
Molecular Formula	C6H9BrN2O4
Molecular Weight	253.05 g/mol
Synonyms	(S)-4-Bromohomoibotenic acid; (S)-4-Bromo-2-(3,4-dihydroxyisoxazol-5-yl)glycine; (S)-4-Br-HIBO; 4-Bromo-HIBO; (S)-4-Bromo-2-(3,4-dihydroxy-4H-isoxazol-5-yl)acetic acid; Bromohomoibotenate; (S)-Bromo-HIBO; 121313-15-3
EINECS	Contact for details

Quality Control

Our (S)-4-Bromo-Homo-Ibotenic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for advanced research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.