Description

2,5-Dioxo-1-(3-(Pyridin-2-Yldisulfanyl)Propanoyloxy)Pyrrolidine-3-Sulfonic Acid is a specialized heterocyclic sulfonic acid derivative featuring a cleavable disulfide linker, making it a valuable intermediate for advanced chemical synthesis. Its molecular architecture is engineered to facilitate controlled conjugation and release mechanisms in complex formulations. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, biochemical probes, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prodrugs and targeted drug delivery systems, leveraging its cleavable disulfide bond for controlled release.
• Bioconjugation Reagent: Used for the site-specific modification of peptides, proteins, and antibodies to create stable or stimuli-responsive conjugates.
• Crosslinking Agent: Employed in polymer chemistry and material science to introduce disulfide linkages, imparting redox-responsive properties to hydrogels and other polymeric networks.
• Biochemical Research: Serves as a tool compound in studying thiol-disulfide exchange reactions and redox biology.
• Surface Functionalization: Applied to modify surfaces for biosensor development and diagnostic assay platforms.

Basic Information

Product Name	2,5-Dioxo-1-(3-(Pyridin-2-Yldisulfanyl)Propanoyloxy)Pyrrolidine-3-Sulfonic Acid
CAS No.	121115-30-8
Molecular Formula	C13H12N2O7S3
Molecular Weight	404.44 g/mol
Synonyms	1-(3-(Pyridin-2-yldisulfanyl)propanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid; 3-Sulfo-NHS-SS-Pyridine; N-Hydroxysuccinimide ester of 3-(2-pyridyldithio)propionic acid sulfonate; Sulfo-SPDP; NHS-SS-Pyridine sulfonate; 3-(2-Pyridyldithio)propionyloxysuccinimide sulfonic acid; Pyridyl disulfide propionate NHS ester sulfonate
EINECS	Contact for details

Quality Control

Our 2,5-Dioxo-1-(3-(Pyridin-2-Yldisulfanyl)Propanoyloxy)Pyrrolidine-3-Sulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.