Description

1-Oleoyl-2-(9,10-Dibromostearoyl)Phosphatidylcholine is a synthetic, brominated phospholipid derivative, specifically a phosphatidylcholine analog. This compound is of significant interest in biochemical and biophysical research due to its unique halogenated fatty acyl chain, which alters membrane properties and serves as a reactive handle. It is primarily utilized by researchers and product developers in the life sciences sector for studying membrane dynamics, lipid-protein interactions, and as a precursor for synthesizing specialized liposomes or other lipid-based delivery systems.

Application

• Membrane Biophysics Research: Used as a probe to study the effects of halogenation and chain saturation on lipid bilayer structure, fluidity, and phase behavior.
• Lipidomics & Analytical Standards: Serves as a high-purity reference standard for the identification and quantification of modified phospholipids in complex biological samples.
• Specialized Liposome Formulation: A key component in creating functionalized liposomes for targeted drug delivery or diagnostic applications, where the bromine atoms can enable further chemical conjugation.
• Bioconjugation & Chemical Biology: The dibromo moiety provides a reactive site for cross-linking or attaching fluorescent tags, facilitating the study of lipid trafficking and localization.
• Model System for Oxidative Stress: Employed in studies investigating the impact of lipid halogenation and oxidation on cellular membrane function and signaling pathways.
• Pharmaceutical Intermediate: Acts as a critical synthetic intermediate in the development of novel phospholipid-based therapeutic agents.

Basic Information

Product Name	1-Oleoyl-2-(9,10-Dibromostearoyl)Phosphatidylcholine
CAS No.	120246-71-1
Molecular Formula	C46H87Br2NO8P
Molecular Weight	974.00 g/mol
Synonyms	PC(18:1(9Z)/18:0(9,10-Br2)); 1-Oleoyl-2-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine; (9,10-Dibromostearoyl)oleoyl Phosphatidylcholine; Dibromostearoyl Phosphatidylcholine; Brominated Phosphatidylcholine; L-α-Phosphatidylcholine, 1-oleoyl-2-(9,10-dibromostearoyl)-; 1-Oleoyl-2-(9,10-dibromooctadecanoyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-Oleoyl-2-(9,10-Dibromostearoyl)Phosphatidylcholine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, methanol, DMSO
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.