Description

14(S)-Hydroxy Docosahexaenoic Acid is a specialized, bioactive metabolite of the essential ω-3 fatty acid DHA (docosahexaenoic acid). This compound is of significant interest for its role as a signaling molecule in the resolution of inflammation and other critical physiological processes. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, nutraceutical, and advanced life science sectors for developing novel therapeutic agents and high-purity reference standards.

Application

• Biomedical Research: Critical as a reference standard and bioactive compound for studying specialized pro-resolving mediators (SPMs), inflammation resolution pathways, and neuroprotection.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the research and development of novel anti-inflammatory and pro-resolving therapeutics.
• Nutraceutical Formulation: Used in advanced dietary supplements targeting metabolic health, cognitive function, and inflammatory balance, often in combination with other ω-3 derivatives.
• Cell Culture & Biochemistry: Employed in cell-based assays and biochemical studies to investigate lipid signaling mechanisms and receptor interactions.
• Analytical Standard: Essential for the calibration of analytical equipment (HPLC, LC-MS) and for quality control in the analysis of complex lipid mixtures.

Basic Information

Product Name	14(S)-Hydroxy Docosahexaenoic Acid
CAS No.	119433-37-3
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	14(S)-HDoHE; 14(S)-HDHA; 14S-Hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic Acid; 14(S)-HDoHE; 14S-HDoHE; (14S)-Hydroxydocosa-4Z,7Z,10Z,12E,16Z,19Z-hexaenoic Acid; 14(S)-Hydroxy-DHA; 14-HDoHE
EINECS	Contact for details

Quality Control

Every batch of 14(S)-Hydroxy Docosahexaenoic Acid is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your research or production requirements. A detailed Certificate of Analysis (COA), including purity by HPLC, stereochemical confirmation, and impurity profile, is supplied with each shipment.

Storage

Preserve in a tightly closed container under an inert atmosphere (e.g., argon or nitrogen), protected from light. For long-term stability, store at -20°C or below. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Enantiomeric Excess (Chiral HPLC)	≥ 98% (14S)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.