Description

1,2-Dipalmitoyloxypropyl-3-(2'-Hydroxypropyl-3'-(1'',2''-Dipalmitoylglycerol))Biphosphonate CAS NO 119206-59-6 is a sophisticated, high-purity synthetic phospholipid derivative. This compound is valued for its unique structural properties, which make it an essential component in advanced drug delivery systems and biomimetic research. It is primarily utilized by pharmaceutical R&D teams and manufacturers of specialty chemicals for creating liposomal formulations and other nano-carriers.

Application

• Liposomal Drug Delivery: A key excipient for formulating stable, long-circulating liposomes for targeted cancer therapies and other injectable pharmaceuticals.
• Biomimetic Membrane Research: Used to construct model membranes for studying cell membrane dynamics, protein-lipid interactions, and permeability.
• Diagnostic Reagents: Serves as a functional component in diagnostic kits and assays that utilize lipid-based signal amplification or capture.
• Gene Delivery Vectors: Incorporated into non-viral vector systems (e.g., lipid nanoparticles) for the encapsulation and delivery of nucleic acids (DNA, siRNA, mRNA).
• Cosmetic Actives Carrier: Enhances the skin penetration and stability of active ingredients in high-end cosmetic and dermatological products.
• Specialty Surfactants: Acts as a high-value, biocompatible surfactant for demanding applications in medical devices and biomedical coatings.

Basic Information

Product Name	1,2-Dipalmitoyloxypropyl-3-(2'-Hydroxypropyl-3'-(1'',2''-Dipalmitoylglycerol))Biphosphonate
CAS No.	119206-59-6
Molecular Formula	C79H152O14P2
Molecular Weight	1388.00 g/mol
Synonyms	Bis(1,2-dipalmitoyl-sn-glycero-3-phospho)-sn-glycerol; DPPG analog; 1,2-Dipalmitoylphosphatidylglycerol derivative; Glycerophospholipid, bis-dipalmitoyl; Lipid A analog precursor; Synthetic phospholipid; PGP(16:0/16:0); Phosphatidylglycerophosphate (dipalmitoyl)
EINECS	Contact for details

Quality Control

Every batch of our phospholipid is produced under strict GMP-like conditions and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Quality is verified through multiple orthogonal methods including HPLC, NMR, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, related substances, and residual solvents to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.