Description

Huperzinine is a naturally occurring alkaloid derived from the Chinese club moss *Huperzia serrata*, known for its potent and selective acetylcholinesterase (AChE) inhibitory activity. This makes it a compound of significant interest for research into cognitive function and neurological health. It serves as a critical reference standard and active ingredient for the pharmaceutical, nutraceutical, and research sectors. Professionals in neuroscience, pharmacology, and product development rely on high-purity Huperzinine CAS NO 119188-49-7 for its consistent biological activity and quality.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and quality control of pharmaceutical products and herbal extracts in compliance with pharmacopeial methods.
• Cognitive Health Research: Serves as a key investigational compound in preclinical and clinical studies targeting memory enhancement and neuroprotective pathways.
• Dietary Supplement Formulation: Incorporated as an active ingredient in high-end nutraceutical products aimed at supporting mental clarity and focus.
• Acetylcholinesterase (AChE) Inhibition Studies: Essential for biochemical and pharmacological research to study enzyme kinetics and screen for new therapeutic agents.
• Neuroscience & Pharmacology: Utilized in academic and industrial R&D to explore mechanisms related to Alzheimer's disease and other cognitive disorders.
• Herbal Extract Standardization: Employed to standardize and quantify the potency of *Huperzia serrata* extracts, ensuring batch-to-batch consistency for manufacturers.

Basic Information

Product Name	Huperzinine
CAS No.	119188-49-7
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	Huperzine A; Selagine; (-)-Huperzine A; (5R,9R,11E)-5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one; ZT-1 (prodrug form); L-Huperzine A; Neurotrophic agent
EINECS	Contact for details

Quality Control

Every batch of our Huperzinine is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to support your regulatory and research requirements. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.