Description

Diethylenetriaminepentaacetic Acid Alpha,ω-Bis(Biocytinamide) is a specialized, high-purity chelating agent derivative designed for advanced biochemical and diagnostic applications. This compound matters for its unique bifunctional structure, which combines the powerful metal-chelating properties of DTPA with the biotin-binding affinity of biocytin, enabling precise conjugation and targeting. It is primarily needed by researchers and manufacturers in the fields of molecular diagnostics, advanced imaging, and targeted drug delivery systems.

Application

• Molecular Diagnostics: Used as a key component in the development of sensitive assay platforms, including ELISA and lateral flow tests, for the detection of specific biomarkers.
• Advanced Imaging Probes: Serves as a bifunctional linker for attaching contrast agents (e.g., gadolinium complexes for MRI) to targeting molecules like antibodies or peptides.
• Targeted Therapeutic Conjugates: Facilitates the creation of drug-antibody conjugates (ADCs) or radiopharmaceuticals by linking cytotoxic payloads or radioisotopes to biological targeting vectors.
• Affinity Chromatography: Immobilized on solid supports to create resins for the purification of biotinylated proteins or other biomolecules via streptavidin-biotin interaction.
• Cell Biology & Microscopy: Employed in fluorescent labeling strategies for tracking cellular uptake, receptor localization, and intracellular trafficking.
• Biosensor Development: Integrated into sensor surfaces to enhance specificity and signal amplification for detecting analytes in complex biological samples.

Basic Information

Product Name	Diethylenetriaminepentaacetic Acid Alpha,ω-Bis(Biocytinamide)
CAS No.	118896-98-3
Molecular Formula	C38H62N10O16S2
Molecular Weight	967.08 g/mol
Synonyms	DTPA-Bis(biocytin); DTPA-Bis(biocytinamide); α,ω-Bis(biocytinamido)DTPA; DTPA-bis(biocytin) pentaacetic acid; N,N-Bis[2-[bis(carboxymethyl)amino]ethyl]-N-[2-[[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyl]amino]ethyl]glycine; Biocytinamido-DTPA; DTPA-BBCA; Chelator-Biotin Conjugate
EINECS	Contact for details

Quality Control

Our Diethylenetriaminepentaacetic Acid Alpha,ω-Bis(Biocytinamide) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.