Description

[(2R,3R,4R,5R)-5-(5-Fluoro-2,4-Dioxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxo Lan-2-Yl]Methyl Octanoate is a high-purity, fluorinated pyrimidine nucleoside derivative, a critical building block in advanced pharmaceutical synthesis. This compound is valued for its role as a key intermediate in the development of novel antiviral and anticancer therapeutics, where precise stereochemistry and purity are paramount. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of nucleoside analogs and prodrug development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analog drugs.
• Antiviral Drug Research: Used in the R&D of prodrugs targeting viral polymerases for diseases such as hepatitis and herpes.
• Oncology Research: Serves as a building block for developing chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in studies of enzyme kinetics and mechanisms involving modified nucleosides.
• Prodrug Development: Utilized to create lipophilic prodrug forms of active nucleosides to enhance bioavailability and cellular uptake.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	[(2R,3R,4R,5R)-5-(5-Fluoro-2,4-Dioxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxo Lan-2-Yl]Methyl Octanoate
CAS No.	118694-10-3
Molecular Formula	C18H25FN2O8
Molecular Weight	416.40 g/mol
Synonyms	5-Fluoro-2'-deoxyuridine Octanoate; 5-Fluoro-2'-deoxyuridine 5'-Octanoate; FdUrd Octanoate; 1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(octanoyloxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 5-Fluoro-2'-deoxyuridine-5'-O-octanoate; Octanoyl Fluorodeoxyuridine; 5-FdUrd Octanoate; 5-Fluoro-2'-deoxyuridine 5'-O-octanoate
EINECS	Contact for details

Quality Control

Our [(2R,3R,4R,5R)-5-(5-Fluoro-2,4-Dioxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxo Lan-2-Yl]Methyl Octanoate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.