Description

n-(4-((3-(2,4-Diamino-1,6-Dihydro-6-Oxo-5-Pyrimidinyl)Propyl)Amino)Benzoyl)Glutamic Acid CAS NO 118252-44-1 is a sophisticated heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its molecular structure, featuring a pyrimidine core linked to glutamic acid, makes it a valuable intermediate for synthesizing novel therapeutic agents. This high-purity chemical is primarily utilized by research institutions and pharmaceutical companies focused on oncology and metabolic disease treatment pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted anti-cancer drugs and enzyme inhibitors.
• Biochemical Research: Used in studies investigating folate metabolism and related cellular pathways.
• Medicinal Chemistry: Serves as a scaffold for developing new chemical entities (NCEs) with potential therapeutic activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug design.

Basic Information

Product Name	n-(4-((3-(2,4-Diamino-1,6-Dihydro-6-Oxo-5-Pyrimidinyl)Propyl)Amino)Benzoyl)Glutamic Acid
CAS No.	118252-44-1
Molecular Formula	C19H24N8O5
Molecular Weight	444.45 g/mol
Synonyms	4-[[3-(2,4-Diamino-6-oxo-1,6-dihydro-5-pyrimidinyl)propyl]amino]benzoyl-L-glutamic acid; L-Glutamic acid, N-[4-[[3-(2,4-diamino-6-oxo-1,6-dihydro-5-pyrimidinyl)propyl]amino]benzoyl]-; (2S)-2-[[4-[[3-(2,4-diamino-6-oxo-1H-pyrimidin-5-yl)propyl]amino]benzoyl]amino]pentanedioic acid; Pteroic acid derivative; Glutamyl-p-aminobenzoyl-polyamine conjugate
EINECS	Contact for details

Quality Control

Our n-(4-((3-(2,4-Diamino-1,6-Dihydro-6-Oxo-5-Pyrimidinyl)Propyl)Amino)Benzoyl)Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.