Description

D-Myo-Inositol 1,4,5-Tris(Thiophosphoric Acid) is a high-purity, synthetic derivative of inositol phosphate, specifically engineered for advanced biochemical research and pharmaceutical development. This compound serves as a critical tool molecule for studying intracellular signaling pathways, particularly those involving inositol trisphosphate (IP3) receptors and calcium mobilization. It is essential for researchers and manufacturers in the fields of cell biology, neuropharmacology, and drug discovery who require precise and reliable biochemical probes. Our supply ensures consistent quality and stability for sensitive experimental and developmental applications.

Application

• Biochemical Research: Used as a potent and stable analog of D-myo-inositol 1,4,5-trisphosphate (IP3) to investigate phosphoinositide signaling cascades and calcium release mechanisms in cellular systems.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of therapeutics targeting neurological disorders, cardiovascular diseases, and metabolic conditions.
• Enzyme Studies: Employed as a substrate or inhibitor in assays for kinases, phosphatases, and phospholipases involved in inositol phosphate metabolism.
• Cell Signaling Probes: Utilized in the development of diagnostic tools and fluorescent probes to visualize and quantify IP3 receptor activity and localization.
• Academic Research: A vital reagent for university and institutional labs studying fundamental processes in cell physiology, apoptosis, and hormone action.
• GMP Manufacturing: Potential use as a high-purity starting material or reference compound in the synthesis of active pharmaceutical ingredients (APIs) under controlled conditions.

Basic Information

Product Name	D-Myo-Inositol 1,4,5-Tris(Thiophosphoric Acid)
CAS No.	118245-69-5
Molecular Formula	C6H15O15P3S3
Molecular Weight	564.30 g/mol
Synonyms	D-myo-Inositol 1,4,5-Trisphosphorothioate; Ins(1,4,5)PS3; 1D-myo-Inositol 1,4,5-trisphosphorothioic acid; IP3 Thiophosphate Analog; Inositol 1,4,5-Tris(Thiophosphate); D-Ins(1,4,5)PS3; Adenophostin A analog (thiophosphate); myo-Inositol 1,4,5-trisphosphorothioate
EINECS	Contact for details

Quality Control

Every batch of D-Myo-Inositol 1,4,5-Tris(Thiophosphoric Acid) is manufactured and analyzed under strict quality protocols to ensure identity, purity, and consistency for research use. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay purity, chiral purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% (D-isomer)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.