Description

2-Fluoro-2-Deoxy-D-Glucose, [5,6-3H] is a tritium-labeled analog of the widely used metabolic tracer 2-Fluoro-2-deoxy-D-glucose (FDG). This compound is critical for advanced research requiring high-sensitivity detection and quantification of glucose uptake and metabolism in biological systems. It is an essential tool for researchers in pharmaceutical development, oncology, and neuroscience who require precise, long-term tracking of metabolic pathways.

Application

• Metabolic Pathway Research: Used as a radiolabeled tracer to study glucose uptake, hexokinase activity, and glycolysis in cell cultures and tissue samples.
• Drug Discovery & Development: Employed in in vitro assays to screen and evaluate the efficacy of novel anticancer and metabolic disorder therapeutics.
• Biochemical Mechanism Studies: Facilitates the investigation of enzyme kinetics and inhibitor effects within the glucose metabolic network.
• Autoradiography & Imaging Support: Serves as a precursor or reference standard in the development and validation of quantitative autoradiography techniques.
• Quality Control for PET Tracers: Acts as a reference material in the synthesis and quality assurance of Fluorodeoxyglucose F 18 (FDG) for Positron Emission Tomography (PET).

Basic Information

Product Name	2-Fluoro-2-Deoxy-D-Glucose, [5,6-3H]
CAS No.	118121-49-6
Molecular Formula	C6H11FO5 (tritium labeled at positions 5,6)
Molecular Weight	Contact for details
Synonyms	2-FDG-[5,6-3H]; [5,6-3H]-2-Fluoro-2-deoxy-D-glucose; Tritiated FDG; FDG-[3H]; 2-Deoxy-2-fluoro-D-[5,6-3H]glucose; 2-Fluoro-2-deoxy-D-[5,6-3H]glucose; [3H]FDG
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-2-Deoxy-D-Glucose, [5,6-3H] is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing radionuclidic purity, radiochemical purity, chemical purity, and specific activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. Store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Radiochemical Purity (HPLC)	≥ 95%
Specific Activity	Contact for details
Chemical Purity (HPLC)	≥ 90%
Solvent	Ethanol:Water solution
Concentration	1 mCi/mL (typical)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.