Description

Collagenase Chromophore-Substrate is a specialized biochemical reagent designed for the sensitive and specific detection of collagenase enzyme activity. This compound serves as a critical tool in enzymatic research and assay development, offering a chromogenic or fluorogenic signal upon cleavage by collagenase. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and biomedical research sectors who require precise measurement of collagenase for drug development, tissue engineering, and diagnostic applications.

Application

• Enzymatic Activity Assays: Primary use as a selective substrate in spectrophotometric or fluorometric assays to quantify collagenase activity in research samples.
• Drug Discovery & Screening: Used in high-throughput screening (HTS) platforms to identify and evaluate potential collagenase inhibitors for therapeutic development.
• Biomedical Research: Facilitates studies on extracellular matrix (ECM) remodeling, wound healing, and diseases involving abnormal collagen degradation.
• Quality Control (QC) Testing: Employed in the QC of collagenase preparations, including those used in tissue dissociation and cell isolation procedures.
• Diagnostic Development: Serves as a key component in developing clinical diagnostic kits for conditions related to collagen metabolism.
• Tissue Engineering: Used to monitor and control collagenase activity in processes for decellularizing tissues or creating biological scaffolds.

Basic Information

Product Name	Collagenase Chromophore-Substrate
CAS No.	118081-33-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Collagenase Substrate; Chromogenic Collagenase Substrate; Fluorogenic Collagenase Substrate; Collagenase Activity Probe; Collagenase Detection Reagent; ECM Degradation Substrate; Matrix Metalloproteinase (MMP) Substrate (Collagenase-specific); Synthetic Collagenase Peptide Substrate
EINECS	Contact for details

Quality Control

Our Collagenase Chromophore-Substrate is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and performance reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and functional validation in enzymatic assays. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at recommended temperatures (typically 2-8°C or -20°C for long-term storage; refer to specific COA). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Solid (Powder or Lyophilized)
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Functional Activity	Validated in collagenase assay system
Solubility	Soluble in specified assay buffer (e.g., DMSO, aqueous buffer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.