Description

Protein Tyrosine Phosphatase Substrate (Monophosphorylated) is a high-purity, synthetic phosphopeptide specifically designed for biochemical research and assay development. This compound serves as a critical tool for studying the activity, kinetics, and inhibition of protein tyrosine phosphatases (PTPs), enzymes pivotal in cellular signaling pathways. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors engaged in drug discovery, target validation, and fundamental cell biology studies.

Application

• Enzyme Activity Assays: Primary substrate for quantifying the catalytic activity of various protein tyrosine phosphatases (PTPs) in vitro.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel PTP inhibitors for therapeutic development.
• Kinetic & Mechanistic Studies: Enables detailed analysis of enzyme kinetics (Km, Vmax), substrate specificity, and catalytic mechanisms of PTP family members.
• Diagnostic Kit Development: A key component in the formulation of diagnostic kits and reagents for research into signaling dysregulation.
• Biochemical Research: Fundamental tool for academic and industrial research into cell signaling, oncology, immunology, and metabolic disorders.
• Quality Control: Serves as a reference standard and control material for ensuring the consistency and performance of PTP-related assays and reagents.

Basic Information

Product Name	Protein Tyrosine Phosphatase Substrate (Monophosphorylated)
CAS No.	117872-62-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Monophosphotyrosine Peptide Substrate; PTP Substrate; Phosphopeptide PTP Substrate; Tyrosine Phosphatase Substrate; pTyr Peptide; END(pY)INASL; EGFR (988-993) (phospho Y992); Epidermal Growth Factor Receptor Peptide (988-993) (phospho Y992); Substrate for Protein Tyrosine Phosphatase
EINECS	Contact for details

Quality Control

Our Protein Tyrosine Phosphatase Substrate is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and MS for identity confirmation. A detailed Certificate of Analysis (COA) is provided, documenting the specifications and test results. We adhere to a quality management system to support our commitment to reliability for the global research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or buffer solutions
Biological Activity	Functional as a PTP substrate

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.