Description

o-Bromoacetylthiamine is a key synthetic intermediate and a chemically modified derivative of Vitamin B1 (Thiamine). This compound is of significant value in pharmaceutical research and fine chemical synthesis due to its reactive bromoacetyl group, which allows for targeted molecular modifications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries for developing novel active compounds and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel thiamine analogs and prodrugs with potential therapeutic applications.
• Biochemical Research: Used as a derivatization agent or a precursor in the study of enzyme mechanisms and metabolic pathways involving thiamine.
• Agrochemical Synthesis: Serves as an intermediate in the development of new crop protection agents and plant growth regulators.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical entities.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	o-Bromoacetylthiamine
CAS No.	117826-71-8
Molecular Formula	C14H17BrN4O3S
Molecular Weight	401.28 g/mol
Synonyms	2-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-bromoacetyl)-4-methyl-1,3-thiazol-3-ium; Bromoacetylthiamine; Thiamine bromoacetate; o-Bromoacetyl vitamin B1; 5-(2-Bromoacetyl)-3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methylthiazolium; 2-Bromoacetylthiamine
EINECS	Contact for details

Quality Control

Our o-Bromoacetylthiamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.