Description

n-Succinyl-Alanyl-Methionyl-S-Benzylcysteine-4-Nitroanilide CAS NO 117823-37-7 is a synthetic peptide substrate designed for enzymatic research and diagnostic applications. This compound is critical for the specific and sensitive detection of protease activity, particularly in biochemical assays. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic kit production industries for studying enzyme kinetics and developing high-throughput screening methods.

Application

• Protease Activity Assays: A specific chromogenic substrate for measuring the activity of various proteolytic enzymes in research settings.
• Diagnostic Kit Development: Used as a key reagent in the formulation of diagnostic kits for detecting specific enzyme markers related to disease states.
• Biochemical Research: Essential for studying enzyme mechanisms, inhibition, and kinetics in academic and industrial laboratories.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential protease inhibitor drug candidates.
• Quality Control in Biomanufacturing: Used to monitor and validate the activity of enzyme batches used in biopharmaceutical production processes.

Basic Information

Product Name	n-Succinyl-Alanyl-Methionyl-S-Benzylcysteine-4-Nitroanilide
CAS No.	117823-37-7
Molecular Formula	C30H38N6O9S2
Molecular Weight	690.79 g/mol
Synonyms	Suc-Ala-Met-S-Bzl-Cys-pNA; Suc-AMC-pNA; Succinyl-Ala-Met-S-Benzyl-Cys-4-Nitroanilide; Protease Substrate 117823-37-7; N-Succinyl-L-Alanyl-L-Methionyl-S-Benzyl-L-Cysteine 4-Nitroanilide; Chromogenic Protease Substrate; S-Benzylcysteine Nitroanilide Derivative
EINECS	Contact for details

Quality Control

Our n-Succinyl-Alanyl-Methionyl-S-Benzylcysteine-4-Nitroanilide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.