Description

1,4-Bis(Glutathion-S-Yl)-1,2,3,4-Tetrachlorobuta-1,3-Diene is a specialized biochemical derivative of glutathione, a critical tripeptide antioxidant. This compound is of significant interest in advanced research due to its role as a potential biomarker or model compound for studying the metabolic pathways and detoxification mechanisms of halogenated hydrocarbons. It is primarily utilized by research institutions and pharmaceutical development laboratories focused on toxicology, metabolomics, and the biochemical analysis of glutathione S-conjugates.

Application

• Biochemical Research: Serves as a reference standard or model compound in studies of glutathione-mediated detoxification pathways.
• Toxicology Studies: Used to investigate the metabolic fate and adduct formation of chlorinated butadiene derivatives in biological systems.
• Analytical Chemistry: Employed as a high-purity standard for calibrating analytical instruments like HPLC-MS or LC-MS/MS in metabolite identification.
• Metabolomics: Acts as a specific biomarker candidate in research aimed at understanding exposure to certain industrial chemicals.
• Pharmaceutical Development: Used in early-stage research exploring drug metabolism and the formation of reactive intermediates.

Basic Information

Product Name	1,4-Bis(Glutathion-S-Yl)-1,2,3,4-Tetrachlorobuta-1,3-Diene
CAS No.	117707-49-0
Molecular Formula	C₂₀H₂₈Cl₄N₆O₁₂S₂
Molecular Weight	~ 774.4 g/mol (Contact for exact details)
Synonyms	1,4-Bis(glutathion-S-yl)-1,2,3,4-tetrachloro-1,3-butadiene; 1,2,3,4-Tetrachloro-1,4-bis(glutathion-S-yl)buta-1,3-diene; TCBD-GSH Diconjugate; Tetrachlorobuta-1,3-diene bis-glutathione conjugate; 1,4-Bis-(S-glutathionyl)-1,2,3,4-tetrachlorobuta-1,3-diene; GSH conjugate of Tetrachlorobuta-1,3-diene
EINECS	Contact for details

Quality Control

Our 1,4-Bis(Glutathion-S-Yl)-1,2,3,4-Tetrachlorobuta-1,3-Diene is produced and handled under strict quality protocols suitable for research applications. Each batch is analyzed to ensure high purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification tests (e.g., HPLC, MS) is provided with every shipment to guarantee consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Contact for higher grades)
Water Content (KF)	≤ 3.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.