Description

4-Chlorobenzoyl Coenzyme A is a specialized biochemical reagent, a coenzyme A derivative of 4-chlorobenzoic acid, with the CAS registry number 117380-98-0. This compound serves as a critical substrate and intermediate in enzymatic research, particularly for studying acyltransferase and synthetase activities. It is essential for researchers and manufacturers in pharmaceutical development, biochemical research, and metabolic pathway analysis.

Application

• Enzymology Research: As a key substrate for studying acyl-CoA synthetases and transferases involved in xenobiotic metabolism.
• Drug Metabolism Studies: Used to investigate the conjugation and detoxification pathways of chlorinated aromatic compounds in vitro.
• Biocatalyst Development: Serves as an acyl donor in enzymatic synthesis for producing novel chiral intermediates.
• Biochemical Assay Standard: Acts as a reference standard in HPLC and LC-MS assays to quantify enzyme activity and metabolic products.
• Academic Research: Utilized in university and institutional labs for fundamental research on fatty acid and secondary metabolism.
• Pharmaceutical Intermediates: Potential use in the synthesis of more complex bioactive molecules and prodrugs.

Basic Information

Product Name	4-Chlorobenzoyl Coenzyme A
CAS No.	117380-98-0
Molecular Formula	C28H40ClN7O17P3S
Molecular Weight	914.09 g/mol
Synonyms	4-Chlorobenzoyl-CoA; p-Chlorobenzoyl Coenzyme A; Coenzyme A, S-(4-chlorobenzoate); 4-Chlorobenzoyl-CoA lithium salt; 4-Chlorobenzoyl-coenzyme A lithium salt; p-Chlorobenzoyl-CoA; S-(4-Chlorobenzoyl)coenzyme A; 4-CBA-CoA
EINECS	Contact for details

Quality Control

Our 4-Chlorobenzoyl Coenzyme A is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.