Description

14,20,25-Trihydroxy-3β-(Phosphonooxy)-5β-Cholest-7-En-6-One is a high-purity, synthetic steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of novel bioactive molecules targeting metabolic and endocrine pathways. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in steroid chemistry, drug discovery, and analytical method development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based therapeutics and prodrugs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) of related steroid compounds.
• Biochemical Research: Employed in studies investigating steroid metabolism, enzyme inhibition, and receptor binding activities.
• Academic Research: Serves as a substrate or reagent in university and institutional research projects focused on organic synthesis and medicinal chemistry.
• Process Development: Used in scaling up synthetic routes for new chemical entities (NCEs) within pilot plants.

Basic Information

Product Name	14,20,25-Trihydroxy-3β-(Phosphonooxy)-5β-Cholest-7-En-6-One
CAS No.	117176-37-1
Molecular Formula	C27H45O8P
Molecular Weight	528.61 g/mol
Synonyms	14,20,25-Trihydroxy-3β-(phosphonooxy)-5β-cholest-7-en-6-one; 3β-Phosphoryloxy-14,20,25-trihydroxy-5β-cholest-7-en-6-one; 5β-Cholest-7-en-6-one, 14,20,25-trihydroxy-3β-(phosphonooxy)-; 117176-37-1; Steroid phosphate intermediate; Cholestane derivative phosphate ester
EINECS	Contact for details

Quality Control

Our 14,20,25-Trihydroxy-3β-(Phosphonooxy)-5β-Cholest-7-En-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.