Description

12-((4-Azido-2-Nitrophenyl)Amino)Dodecanoyl-Gm1 is a specialized, chemically modified ganglioside derivative designed for advanced biochemical research and development. This compound is critical for studying cell membrane dynamics, receptor interactions, and signal transduction pathways due to its photoactivatable azido group. It is primarily utilized by research institutions and pharmaceutical companies engaged in neurobiology, immunology, and the development of targeted therapeutic agents.

Application

• Biochemical Research Probe: Used as a photoaffinity labeling agent to study ganglioside-protein interactions and membrane microdomains (lipid rafts).
• Neuroscience Studies: Essential for investigating the role of GM1 ganglioside in neuronal development, repair, and neurodegenerative disease models.
• Immunology & Vaccine Development: Serves as a hapten or antigenic component in the development of conjugate vaccines and immunological assays.
• Drug Delivery Systems: Employed in the design of targeted liposomal or nanoparticle-based delivery systems for crossing the blood-brain barrier.
• Diagnostic Reagent Synthesis: Acts as a key intermediate in the synthesis of labeled probes for fluorescence microscopy, flow cytometry, and ELISA.
• Glycobiology Research: A vital tool for exploring glycosphingolipid metabolism, trafficking, and their function in cell adhesion and recognition.

Basic Information

Item	Detail
Product Name	12-((4-Azido-2-Nitrophenyl)Amino)Dodecanoyl-Gm1
CAS No.	116926-94-4
Molecular Formula	C59H100N6O23
Molecular Weight	1261.45 g/mol
Synonyms	GM1 Ganglioside, Azido Derivative; N-(12-((4-Azido-2-nitrophenyl)amino)dodecanoyl)-GM1; ANP-Dodecanoyl-GM1; 4-Azido-2-nitrophenylamino-dodecanoyl-GM1; Photoactivatable GM1; GM1-ANPA; Azidoaryl-GM1; Ganglioside GM1 Azido Label
EINECS	Contact for details

Quality Control

Every batch of 12-((4-Azido-2-Nitrophenyl)Amino)Dodecanoyl-Gm1 is manufactured and analyzed under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Our quality commitment includes comprehensive analytical characterization via HPLC, MS, and NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and stability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Chloroform/Methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.