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1,2-Ditetradecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt CAS NO 116870-30-5
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CAS No.:116870-30-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Ditetradecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt is a high-purity, synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (PG) with two myristoyl (C14:0) fatty acid chains. This compound is a critical building block for constructing biomimetic membranes and liposomal drug delivery systems, offering excellent batch-to-batch consistency. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science industries for applications requiring precise lipid composition and stability.
Application
- Liposomal Drug Formulation: A key excipient for creating stable, anionic liposomes for targeted drug delivery, particularly for anticancer and antifungal therapeutics.
- Biomimetic Membrane Research: Used to construct model cell membranes (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and fusion processes.
- Pulmonary Surfactant Mimetics: A component in synthetic lung surfactant research due to its structural similarity to natural surfactant phospholipids.
- Diagnostic Assay Development: Serves as a coating or capture agent in biosensors and immunoassays that leverage lipid-protein interactions.
- Cosmetic & Dermal Delivery Systems: Incorporated into nanocarriers like transfersomes and ethosomes for enhanced skin penetration of active ingredients.
- Cell Culture & Cryopreservation: Used as a supplement in specialized cell culture media and as a cryoprotectant agent for stabilizing biological membranes.
Basic Information
| Product Name | 1,2-Ditetradecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt |
| CAS No. | 116870-30-5 |
| Molecular Formula | C34H66NaO10P |
| Molecular Weight | 688.84 g/mol |
| Synonyms | 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt; DMPG-Na; PG(14:0/14:0) Sodium Salt; 1,2-Ditetradecanoylphosphatidylglycerol Sodium Salt; Phosphatidylglycerol (14:0) Sodium Salt; DMPG Sodium Salt; 1,2-Dimyristoylphosphatidylglycerol Sodium Salt; (Rac)-1,2-Dimyristoyl-3-phosphatidylglycerol Sodium Salt |
| EINECS | Contact for details |
Quality Control
Our 1,2-Ditetradecanoyl-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Sodium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, related substances, and critical parameters are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | ≤ 10 ppm |
| Bacterial Endotoxins | < 10 EU/mg (if applicable) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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