Description

20-Hepe CAS NO 116477-57-7 is a specialized eicosanoid derivative, specifically a 20-hydroxy metabolite of eicosapentaenoic acid (EPA), with significant biological activity. This high-purity compound is critical for advanced research in lipid signaling and inflammation pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers focused on metabolic and inflammatory disease models.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of eicosanoid biology, inflammation resolution, and specialized pro-resolving mediator (SPM) pathways.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the discovery of novel therapeutics targeting metabolic syndrome, cardiovascular diseases, and chronic inflammatory conditions.
• Diagnostic Assays: Employed as a calibration standard in mass spectrometry (LC-MS/MS) and immunoassay kits for the quantitative analysis of oxylipins in biological samples.
• Cell Culture & Biochemistry: Applied in *in vitro* studies to investigate receptor-mediated signaling, gene expression regulation, and cellular metabolism related to EPA-derived metabolites.
• Nutritional Science Research: Investigated for its role as a bioactive metabolite of ω-3 fatty acids, supporting research into the health benefits of fish oil and dietary supplements.

Basic Information

Product Name	20-Hepe
CAS No.	116477-57-7
Molecular Formula	C₂₀H₃₀O₃
Molecular Weight	318.45 g/mol
Synonyms	20-Hydroxyeicosapentaenoic acid; 20-HEPE; 20-Hydroxy-5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid; 20-Hydroxyicosa-5,8,11,14,17-pentaenoic acid; (5Z,8Z,11Z,14Z,17Z)-20-Hydroxyicosa-5,8,11,14,17-pentaenoic acid; EPA metabolite 20-HEPE; 20-Hydroxy EPA
EINECS	Contact for details

Quality Control

Every batch of 20-Hepe (CAS 116477-57-7) is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including HPLC chromatograms and mass spectrometry data, to verify identity and purity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for all shipments, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 98% (by GC or HPLC)
Solubility	Soluble in ethanol, DMSO, methanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.