Description

1-Palmitylthio-2-Palmitoylamido-1,2-Dideoxy-Sn-Glycero-3-Phosphocholine CAS NO 116457-99-9 is a high-purity synthetic phospholipid derivative, specifically a thioether-linked phosphatidylcholine analog. This compound is a critical building block for advanced lipid-based research and formulation, offering a stable, chemically defined structure for creating model membranes and delivery systems. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and advanced materials sectors.

Application

• Liposome and Nanoparticle Formulation: As a key structural lipid for creating stable, targeted drug delivery vesicles with modified surface properties.
• Biomimetic Membrane Research: For constructing defined model membranes (e.g., supported lipid bilayers) to study protein-lipid interactions, membrane fluidity, and signaling.
• Cell Biology & Biochemistry: As a tool compound for investigating lipid metabolism, raft formation, and the role of specific lipid modifications in cellular processes.
• Diagnostic Reagent Development: In the formulation of lipid components for diagnostic assays and imaging contrast agents.
• Cosmetic & Dermal Delivery Systems: As an ingredient in high-end cosmetic formulations designed for enhanced skin penetration and stabilization of active ingredients.
• Chemical Biology Probes: Serving as a precursor for synthesizing labeled or functionalized lipids for tracking and detection studies.

Basic Information

Product Name	1-Palmitylthio-2-Palmitoylamido-1,2-Dideoxy-Sn-Glycero-3-Phosphocholine
CAS No.	116457-99-9
Molecular Formula	C40H81N2O6PS
Molecular Weight	749.12 g/mol
Synonyms	1-Hexadecylthio-2-palmitamido-1,2-dideoxy-sn-glycero-3-phosphocholine; S-Hexadecyl-2-palmitamido-1,2-dideoxy-sn-glycero-3-phosphocholine; Thioether PC Lipid; 1-Palmitoylthio-2-palmitoyl-sn-glycero-3-phosphocholine (common name variant); S-Palmitoyl Phosphatidylcholine analog; C16 Thioalkyl Phosphatidylcholine; Lipid 116457-99-9; S-Alkyl Phospholipid
EINECS	Contact for details

Quality Control

We supply 1-Palmitylthio-2-Palmitoylamido-1,2-Dideoxy-Sn-Glycero-3-Phosphocholine to high-purity standards suitable for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure batch-to-batch consistency and reliability. Certificates of Analysis (COA) detailing specific results for purity, identity, and related substances are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.