Description

3-(3-Iodo-4-Azido)Phenethyl-1-Propyl-8-Cyclopentylxanthine is a specialized xanthine derivative designed for advanced biochemical and pharmacological research. This compound is valued for its role as a potent and selective adenosine receptor antagonist, making it a critical tool for studying receptor signaling pathways and developing new therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, cardiovascular research, and drug discovery programs.

Application

• Adenosine Receptor Research: Serves as a key pharmacological probe for characterizing and antagonizing specific adenosine receptor subtypes (A1, A2A, A2B, A3) in vitro and in vivo.
• Neuropharmacology Studies: Used to investigate the role of adenosine signaling in neurological disorders, including Parkinson's disease, neuropathic pain, and ischemia.
• Cardiovascular Research: Applied in studies exploring heart rate regulation, myocardial protection, and vascular tone modulation mediated by adenosine receptors.
• Drug Discovery & Development: Acts as a reference standard and a lead compound scaffold for the design of novel adenosine receptor-targeting pharmaceuticals.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) and binding assays to identify and validate new receptor ligands.
• Academic & Industrial R&D: Essential for basic scientific research in university labs and for applied research in biotech and pharma R&D departments.

Basic Information

Product Name	3-(3-Iodo-4-Azido)Phenethyl-1-Propyl-8-Cyclopentylxanthine
CAS No.	116370-33-3
Molecular Formula	C21H26IN7O2
Molecular Weight	559.38 g/mol
Synonyms	8-Cyclopentyl-3-(3-iodo-4-azidophenethyl)-1-propylxanthine; 8-Cyclopentyl-1-propyl-3-(3-iodo-4-azidophenethyl)xanthine; 3-(3-Iodo-4-azidophenethyl)-8-cyclopentyl-1-propylxanthine; Xanthine amine congener (XAC) derivative; Iodinated azidophenethyl xanthine; Adenosine receptor antagonist 116370-33-3; A1/A2 Adenosine receptor probe
EINECS	Contact for details

Quality Control

Our production of 3-(3-Iodo-4-Azido)Phenethyl-1-Propyl-8-Cyclopentylxanthine adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. All material is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.