Description

Katanosin B CAS NO 116340-02-4 is a complex cyclic depsipeptide antibiotic belonging to the katanosin family. This compound is valued for its potent activity against Gram-positive bacteria, including multidrug-resistant strains such as methicillin-resistant *Staphylococcus aureus* (MRSA) and vancomycin-resistant enterococci (VRE). It is primarily utilized in advanced pharmaceutical research and development for investigating novel antibacterial mechanisms and as a critical reference standard in quality control laboratories.

Application

• Pharmaceutical R&D as a lead compound for developing new anti-infective agents targeting resistant pathogens.
• Microbiological Research for studying bacterial cell wall biosynthesis and the mechanism of action of lipopeptide antibiotics.
• Use as a high-purity biochemical reference standard for analytical method development and validation in QC/QA.
• Investigation in combination therapy studies to combat antibiotic resistance and enhance efficacy.
• Application in academic and institutional research focused on novel antimicrobial peptides.

Basic Information

Product Name	Katanosin B
CAS No.	116340-02-4
Molecular Formula	C72H101N15O22
Molecular Weight	1560.7 g/mol
Synonyms	Katanosin B; Lysobactin; A21978C1; Antibiotic A21978C; Deacetyl-A21978C; (3S)-3-Amino-6-{[(2S,3S,6R)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-Amino-3-phenylpropanamido]-3-phenylpropanamido]-3-hydroxybutanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(4-hydroxyphenyl)propanamido]-6-methylheptanamido]-6-methyl-4-oxoheptanamido}hexanoic Acid
EINECS	Contact for details

Quality Control

Our Katanosin B is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research and reference applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Bacterial Endotoxins	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.