Description

(+)-Alexine CAS NO 116174-63-1 is a high-purity, polyhydroxylated pyrrolizidine alkaloid known for its potent biological activity as a glycosidase inhibitor. This compound is a critical chiral building block and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for the study and synthesis of novel therapeutics targeting metabolic and viral diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of glycosidase inhibitor drugs.
• Biochemical Research: Used as a potent and selective reference standard in enzymatic studies to investigate carbohydrate metabolism.
• Antiviral Agent Development: Serves as a core structure in research for novel antiviral compounds targeting viral glycoprotein processing.
• Metabolic Disorder Research: Applied in studies related to diabetes, lysosomal storage diseases, and cancer metastasis.
• Glycobiology Tool: Essential for probing glycosidase functions and mechanisms in cellular systems.
• Academic & Contract Research: Utilized in university labs and CROs for fundamental and applied medicinal chemistry projects.

Basic Information

Product Name	(+)-Alexine
CAS No.	116174-63-1
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(1R,2R,3R,7S,7aS)-1,2,7-Trihydroxypyrrolizidine; (+)-1,2,7-Trihydroxypyrrolizidine; Alexine; D-Alexine; NSC 326023; (1R,2R,3R,7S,7aR)-Hexahydro-1H-pyrrolizine-1,2,7-triol; Polyhydroxylated Pyrrolizidine Alkaloid
EINECS	Contact for details

Quality Control

Our (+)-Alexine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.