Description

O(6),7-Dimethylguanine is a modified purine nucleobase derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a critical intermediate and reference standard in the study of nucleic acid chemistry, DNA alkylation, and mutagenesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology research, molecular biology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and intermediate in studies of DNA damage, repair mechanisms, and alkylation processes.
• Pharmaceutical Development: Serves as a key building block in the synthesis of nucleoside analogs and potential chemotherapeutic agents.
• Oncology Research: Employed in investigations related to carcinogenesis and the development of targeted cancer therapies.
• Academic Studies: Utilized in university and institutional labs for teaching and advanced research in organic chemistry and molecular biology.
• Diagnostic Reagent Manufacturing: Acts as a precursor or standard in the production of specialized diagnostic kits and assays.

Basic Information

Product Name	O(6),7-Dimethylguanine
CAS No.	116137-82-7
Molecular Formula	C7H9N5O
Molecular Weight	179.18 g/mol
Synonyms	O6,7-Dimethylguanine; 2-Amino-6-methoxy-7-methyl-7H-purin-8-one; 6-Methoxy-7-methylguanine; 7-Methyl-O6-methylguanine; Guanine, O6,7-dimethyl-; 8-Oxo-6-methoxy-7-methylguanine
EINECS	Contact for details

Quality Control

Our O(6),7-Dimethylguanine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.