Description

Succinylglutaminyl-Valyl-Valyl-Alanyl-Alanine-4-Nitroanilide is a specialized synthetic peptide substrate designed for enzymatic research and diagnostic applications. This compound is critical for studying and quantifying the activity of specific proteolytic enzymes, particularly in biochemical and pharmaceutical research. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in enzyme kinetics, assay development, and high-throughput screening.

Application

• Enzyme Substrate for Protease Research: Used as a chromogenic substrate to measure the activity of specific proteases, such as dipeptidyl peptidases or related enzymes, in kinetic studies.
• Biochemical Assay Development: Essential for developing in vitro diagnostic assays to detect and quantify enzyme levels in biological samples.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential enzyme inhibitors for drug discovery.
• Clinical Diagnostics: Integrated into diagnostic kits for the measurement of specific enzyme activities that serve as biomarkers for certain disease states.
• Academic & Industrial Research: A key reagent for fundamental biochemical research into protein digestion, peptide metabolism, and enzyme specificity.

Basic Information

Product Name	Succinylglutaminyl-Valyl-Valyl-Alanyl-Alanine-4-Nitroanilide
CAS No.	115700-57-7
Molecular Formula	C31H46N8O11
Molecular Weight	706.75 g/mol
Synonyms	Suc-Gln-Val-Val-Ala-Ala-pNA; Succinyl-Gln-Val-Val-Ala-Ala-4-nitroanilide; Suc-Gln-VVAA-pNA; Glutaminylpeptide Substrate; Protease Substrate 115700-57-7; DPP Substrate Analog; Chromogenic Peptide Substrate; N-Succinyl-L-glutaminyl-L-valyl-L-valyl-L-alanyl-L-alanine 4-nitroanilide
EINECS	Contact for details

Quality Control

Our Succinylglutaminyl-Valyl-Valyl-Alanyl-Alanine-4-Nitroanilide is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. All batches undergo comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay results, and physical characteristics is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, heat, or light should be avoided to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.