Description

Hecameg CAS NO 115457-83-5 is a high-purity, non-ionic detergent widely recognized for its efficacy in solubilizing membrane proteins. This compound is critical for researchers and manufacturers who require the isolation and stabilization of integral membrane proteins for structural and functional studies. It is an essential reagent in biochemistry, structural biology, and pharmaceutical development, enabling breakthroughs in drug discovery and proteomics.

Application

• Membrane Protein Solubilization: Primary application for extracting and stabilizing integral membrane proteins from biological membranes.
• Structural Biology: Used in the preparation of samples for X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR spectroscopy.
• Biopharmaceutical Production: Facilitates the purification and formulation of membrane protein-based therapeutics and vaccines.
• Diagnostic Assay Development: Serves as a key component in buffers for immunoassays and other diagnostic kits targeting membrane-bound antigens.
• Cell Lysis and Organelle Isolation: Effective in gentle lysis protocols for isolating functional membrane-bound organelles.
• Protein Refolding: Assists in the refolding of denatured membrane proteins into their native, active conformations.

Basic Information

Product Name	Hecameg
CAS No.	115457-83-5
Molecular Formula	C15H32O6
Molecular Weight	308.41 g/mol
Synonyms	Hexaethylene Glycol Monooctyl Ether; n-Octyl-hexaoxyethylene glycol ether; 2-[2-[2-[2-[2-[2-(Octyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; Octyl-HEG; Hecameg Detergent; C8E6; Polyoxyethylene (6) octyl ether
EINECS	Contact for details

Quality Control

Our Hecameg is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including purity assay and critical micelle concentration (CMC) verification. A Certificate of Analysis (COA) detailing specifications such as identity, purity, and absence of critical impurities is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which can affect performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Critical Micelle Concentration (CMC)	Reported
pH (5% solution)	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.