Description

Hexadecyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is a high-purity synthetic glycolipid analog, specifically a long-chain alkyl glycoside derivative of N-acetylglucosamine. This compound serves as a critical non-ionic detergent and biochemical tool for the solubilization, stabilization, and crystallization of membrane proteins, which is essential for structural biology and drug discovery research. It is primarily utilized by biopharmaceutical R&D teams, academic research institutions, and manufacturers of diagnostic reagents requiring high-fidelity membrane protein analysis.

Application

• Membrane Protein Solubilization & Crystallization: A key reagent for extracting and stabilizing integral membrane proteins from lipid bilayers for X-ray crystallography and cryo-EM studies.
• Biochemical Research Reagent: Used in the study of glycobiology, cell surface receptors, and enzymatic processes involving glycosylated structures.
• Pharmaceutical Development: Employed in the formulation and characterization of biologic drug candidates that target membrane-bound proteins.
• Diagnostic Assay Manufacturing: Acts as a stabilizing agent in diagnostic kits that rely on the function of membrane-bound antigens or enzymes.
• Cell Lysis & Organelle Isolation: Facilitates gentle cell membrane disruption for the isolation of intracellular organelles with preserved function.
• Lipid Raft Studies: Used as a tool to investigate the structure and function of cholesterol and sphingolipid-rich membrane microdomains.

Basic Information

Product Name	Hexadecyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside
CAS No.	115414-49-8
Molecular Formula	C₂₄H₄₇NO₇
Molecular Weight	461.64 g/mol
Synonyms	N-Hexadecyl-2-acetamido-2-deoxy-β-D-glucopyranoside; C16-β-GlcNAc; Hexadecyl N-acetyl-β-D-glucosaminide; Palmityl β-N-acetylglucosaminide; 1-O-Hexadecyl-2-acetamido-2-deoxy-β-D-glucopyranose; β-D-GlcNAc-C16; N-Acetyl-β-D-glucosaminide, hexadecyl; Alkyl glycoside detergent
EINECS	Contact for details

Quality Control

Every batch of Hexadecyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets specifications suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your procurement standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term stability, store under an inert atmosphere or in a desiccator to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.