Description

6A-Methylprednisone 21-Acetate is a high-purity synthetic corticosteroid derivative, serving as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its precise chemical structure, which is essential for the research and development of novel anti-inflammatory and immunosuppressive therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers targeting the production of specialized steroid-based APIs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new glucocorticoid receptor modulators.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in regulatory testing.
• Process Chemistry: Employed in scaling up and optimizing manufacturing routes for steroid-based drugs under GMP conditions.

Basic Information

Product Name	6A-Methylprednisone 21-Acetate
CAS No.	115321-98-7
Molecular Formula	C24H30O6
Molecular Weight	414.50 g/mol
Synonyms	6α-Methylprednisone 21-Acetate; 6α-Methyl-17,21-dihydroxypregna-1,4-diene-3,11,20-trione 21-acetate; 6-Methylprednisone 21-acetate; (6α)-21-(Acetyloxy)-6-methyl-17-hydroxypregna-1,4-diene-3,11,20-trione; 6α-Methylprednisone acetate
EINECS	Contact for details

Quality Control

Our 6A-Methylprednisone 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.