Description

Calcitonin, Arg-3-Nitrophenylazido-Lys- is a chemically modified derivative of the peptide hormone calcitonin, incorporating a photoactivatable cross-linking agent. This compound is of significant value in biochemical and pharmacological research for studying hormone-receptor interactions and mapping binding sites. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in advanced peptide research, photolabeling studies, and drug discovery programs.

Application

• Photochemical Cross-linking Studies: Used as a photoaffinity labeling agent to covalently tag and identify calcitonin receptor binding sites.
• Biochemical Research: A critical tool for investigating the structure-activity relationships (SAR) of calcitonin and its analogs.
• Receptor Mapping: Employed to elucidate the three-dimensional architecture of peptide hormone-receptor complexes.
• Drug Discovery Platforms: Serves as a key intermediate or probe in the development of novel therapeutic agents targeting bone metabolism disorders.
• Proteomics and Target Identification: Facilitates the isolation and characterization of proteins that interact with calcitonin pathways.

Basic Information

Product Name	Calcitonin, Arg-3-Nitrophenylazido-Lys-
CAS No.	114451-34-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Arg-3-Nitrophenylazido-Lys-Calcitonin; Calcitonin (Arg-3-nitrophenylazido-Lys); 3-Nitrophenylazido-Lys-Calcitonin; Photoactivatable Calcitonin Derivative; Calcitonin Photoaffinity Label; NPA-Calcitonin; Calcitonin Analog, Photoreactive
EINECS	Contact for details

Quality Control

Our Calcitonin, Arg-3-Nitrophenylazido-Lys- is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques, including HPLC and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store under inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Photoactivity	Functional upon UV irradiation

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.