Description

Triethoxycholesterol Galactose is a specialized synthetic intermediate designed for advanced pharmaceutical and biochemical research. This compound is crucial for the development of targeted drug delivery systems and diagnostic agents due to its unique molecular architecture combining cholesterol and galactose moieties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutics, particularly for liver-targeting applications and advanced lipid nanoparticle formulations.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel cholesterol-conjugated prodrugs and targeted therapeutics.
• Drug Delivery Systems: Functional component in the design of lipid-based nanoparticles (LNPs) and liposomes for enhanced cellular uptake.
• Hepatic Targeting: Utilized in the development of liver-targeting agents that exploit the asialoglycoprotein receptor (ASGPR) pathway.
• Bioconjugation Chemistry: Serves as a versatile linker for attaching therapeutic payloads to carrier molecules via its reactive ethoxy groups.
• Diagnostic Agent Synthesis: Intermediate in the production of contrast agents and molecular probes for imaging applications.
• Biochemical Research: Used in studies investigating membrane biology, lipid metabolism, and carbohydrate-protein interactions.
• Academic & Industrial R&D: Essential material for exploratory chemistry in medicinal chemistry and chemical biology laboratories.

Basic Information

Product Name	Triethoxycholesterol Galactose
CAS No.	114414-35-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cholesterol triethoxy galactose derivative; 3β-[2-(Triethoxy)-3β-cholest-5-en-3-yl β-D-galactopyranoside]; Galactosylated triethoxycholesterol; Triethoxy-cholesterol-galactoside; ASGPR-targeting cholesterol derivative; Chol-Gal(EtO)3; (3β)-Cholest-5-en-3-yl 6-O-[2-(triethoxy)ethyl]-β-D-galactopyranoside
EINECS	Contact for details

Quality Control

Our Triethoxycholesterol Galactose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.