Description

n-[6-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Hexanoyl]-L-Threo-Sphinganine is a highly specialized, fluorescently labeled sphingolipid derivative. This compound is a critical research tool for the study of sphingolipid metabolism, trafficking, and signaling pathways within cellular systems. It is primarily utilized by researchers in the fields of biochemistry, cell biology, and pharmacology. The product is supplied with a high level of purity and batch-to-batch consistency to ensure reliable experimental results.

Application

• Biochemical Research: As a fluorescent probe for tracing and visualizing sphingolipid dynamics in live-cell imaging and microscopy studies.
• Metabolic Pathway Analysis: Investigating the synthesis, degradation, and interconversion of sphingolipids in various disease models.
• Membrane Biology: Studying the role of sphingolipids in membrane structure, lipid raft formation, and cellular compartmentalization.
• Drug Discovery & Pharmacology: Serving as a substrate or tracer in high-throughput screening assays to identify modulators of sphingolipid-related enzymes or transporters.
• Signal Transduction Studies: Elucidating the function of sphingolipids as bioactive signaling molecules in apoptosis, proliferation, and stress responses.
• Academic & Institutional Research: A key reagent for universities and research institutes focused on lipidomics and metabolic disorders.

Basic Information

Product Name	n-[6-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Hexanoyl]-L-Threo-Sphinganine
CAS No.	114301-98-3
Molecular Formula	C30H48N6O7
Molecular Weight	604.74 g/mol
Synonyms	NBD C6-Ceramide (D-erythro); N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine; N-(6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoyl)-D-erythro-sphingosine; C6-NBD Ceramide; Fluorescent Ceramide; NBD-Cer; NBD C6-Cer; 6-((N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine
EINECS	Contact for details

Quality Control

Our n-[6-[(7-Nitro-2-1,3-Benzoxadiazol-4-Yl)Amino]Hexanoyl]-L-Threo-Sphinganine is manufactured under strict quality control protocols to ensure the highest standards for research applications. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and fluorescence properties. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Fluorescence Properties	Ex/Em ~466/536 nm in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.