Description

16-Carboxy-17,18,19,20-Tetranor-14,15-Dihydro-n-Acetylleukotriene E4 is a specialized leukotriene analog, a key intermediate and reference standard in advanced biochemical and pharmaceutical research. This compound is critical for studying inflammatory pathways, receptor binding, and the development of targeted therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on immunology and respiratory medicine.

Application

• Biochemical Research: Serves as a high-purity reference standard and intermediate in the study of leukotriene metabolism and signaling pathways.
• Pharmaceutical Development: Used as a critical building block in the synthesis of novel anti-inflammatory drug candidates and enzyme inhibitors.
• Diagnostic Assays: Employed in the calibration and development of immunoassays (e.g., ELISA) for quantifying leukotriene metabolites in biological samples.
• Academic Research: A vital tool for universities and research institutes investigating the role of eicosanoids in asthma, allergies, and other inflammatory diseases.
• Metabolite Studies: Used in pharmacokinetic and metabolic studies to trace the biotransformation of related leukotriene compounds.

Basic Information

Product Name	16-Carboxy-17,18,19,20-Tetranor-14,15-Dihydro-n-Acetylleukotriene E4
CAS No.	114115-52-5
Molecular Formula	C25H39NO7S
Molecular Weight	497.65 g/mol
Synonyms	16-Carboxy-17,18,19,20-tetranor-14,15-dihydro-N-acetyl-LTE4; 16-COOH-17,18,19,20-tetranor-14,15-dihydro-N-acetyl-LTE4; N-Acetyl-16-carboxy-17,18,19,20-tetranor-14,15-dihydroleukotriene E4; LTE4 metabolite analog; ω-Carboxy-dinor-N-acetyl-LTE4; Tetranordihydro-N-acetyl-LTE4 carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 16-Carboxy-17,18,19,20-Tetranor-14,15-Dihydro-n-Acetylleukotriene E4 is manufactured and analyzed under strict quality management systems to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to moisture and oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure to humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.