Description

3-[[4-[(2,4-Diaminopteridin-6-Yl)Methyl-Methyl-Amino]Benzoyl]Amino]Pro Pyl-Ethoxy-Phosphinic Acid is a high-purity, complex pteridine derivative with significant research and development applications. This compound is valued for its role as a key intermediate or active moiety in the synthesis of advanced pharmaceutical agents, particularly in targeted therapeutic areas. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of novel drug candidates and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antifolate drugs and other therapeutic agents targeting specific enzymatic pathways.
• Biochemical Research: Used as a reference standard or a precursor in studies involving enzyme inhibition, cellular metabolism, and mechanism-of-action investigations.
• Anticancer Drug Development: Investigated for its potential as a core structure in the design of targeted cancer therapies due to its pteridine-based architecture.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in medicinal chemistry and chemical biology.
• Fine Chemical Synthesis: Acts as a specialized intermediate for contract research organizations (CROs) and CDMOs producing custom molecules for client projects.

Basic Information

Product Name	3-[[4-[(2,4-Diaminopteridin-6-Yl)Methyl-Methyl-Amino]Benzoyl]Amino]Pro Pyl-Ethoxy-Phosphinic Acid
CAS No.	113811-51-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-[3-(Ethoxyphosphinyl)propyl]-4-[[(2,4-diaminopteridin-6-yl)methyl-methylamino]methyl]benzamide; Pteridine-6-carboxamide derivative; 4-[[(2,4-Diamino-6-pteridinyl)methyl-methylamino]methyl]-N-[3-(ethoxyphosphinyl)propyl]benzamide; AG 2037 (Research Code); Glycinamide ribonucleotide formyltransferase inhibitor intermediate; Phosphinic acid pteridine analog
EINECS	Contact for details

Quality Control

Our 3-[[4-[(2,4-Diaminopteridin-6-Yl)Methyl-Methyl-Amino]Benzoyl]Amino]Pro Pyl-Ethoxy-Phosphinic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.