Description

H-Arg-Pro-Pna CAS NO 112898-06-3 is a high-purity synthetic peptide derivative, specifically a chromogenic substrate designed for enzymatic activity studies. This compound is critical for biochemical research and diagnostic assay development, offering precise and reliable detection capabilities. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on protease and peptidase enzyme kinetics.

Application

• Biochemical Research: As a specific chromogenic substrate for studying the activity, kinetics, and inhibition of target proteases and peptidases.
• Diagnostic Assay Development: A key component in the formulation of colorimetric diagnostic kits for detecting specific enzyme markers in clinical samples.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and characterize potential therapeutic enzyme inhibitors.
• Quality Control in Biologics: Employed to monitor and quantify protease activity during the production and purification of biopharmaceuticals.
• Academic & Institutional Research: A fundamental tool for investigating proteolytic pathways and enzyme function in life science studies.

Basic Information

Product Name	H-Arg-Pro-Pna
CAS No.	112898-06-3
Molecular Formula	C17H26N8O3
Molecular Weight	390.44 g/mol
Synonyms	H-Arg-Pro-pNA; H-Arg-Pro-4-Nitroanilide; Arg-Pro-pNA; L-Arginyl-L-prolyl 4-nitroanilide; Substrate for Dipeptidyl Peptidase IV (DPP-IV); DPP-IV Substrate; Chromogenic Substrate for DPP-4; 4-Nitroanilide of H-Arg-Pro-OH
EINECS	Contact for details

Quality Control

Our H-Arg-Pro-Pna is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by mass spectrometry (MS) and infrared spectroscopy (IR), and verification of water content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation. For long-term stability, consider storage at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.