Description

P1,P3-Di(Adenosine-5') Triphosphate, Periodate Oxidized is a chemically modified dinucleotide analog, specifically oxidized by periodate to introduce reactive aldehyde groups. This modification is critical for creating stable cross-links or conjugates in biochemical research and diagnostic assay development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in enzymology, molecular probe synthesis, and advanced diagnostic platforms.

Application

• Biochemical Cross-linking Agent: Used to create covalent bonds between biomolecules, such as proteins and nucleic acids, for structural studies or stable complex formation.
• Diagnostic Assay Development: Serves as a key component in the synthesis of labeled probes and conjugates for ELISA, lateral flow assays, and other immunoassay formats.
• Enzyme Substrate Analog: Acts as a modified substrate or inhibitor in enzymatic studies, particularly for ATP-utilizing enzymes like kinases and synthetases.
• Affinity Labeling: Employed to tag and isolate specific proteins or receptors through its reactive aldehyde functionality.
• Nucleic Acid Research: Used in the study of nucleic acid structure, function, and protein-nucleic acid interactions.
• Bioconjugation Chemistry: A versatile intermediate for attaching reporter molecules (e.g., fluorophores, biotin) to other biological molecules.

Basic Information

Product Name	P1,P3-Di(Adenosine-5') Triphosphate, Periodate Oxidized
CAS No.	112897-98-0
Molecular Formula	C20H25N10O16P3
Molecular Weight	802.37 g/mol
Synonyms	Periodate-Oxidized P1,P3-Di(adenosine-5') Triphosphate; P1,P3-Di(adenosine-5')-triphosphate, periodate oxidized; Oxidized Ap3A; P1,P3-Bis(5'-adenosyl) triphosphate, periodate oxidized; Adenosine-5'-[P1,P3-triphosphate], P1,P3-di-, periodate oxidized; Diadenosine triphosphate, periodate oxidized; Ap3A, periodate oxidized; Reactive dinucleotide triphosphate analog
EINECS	Contact for details

Quality Control

Our P1,P3-Di(Adenosine-5') Triphosphate, Periodate Oxidized is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and in-vitro diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0 %
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.