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9-S-(4-Azido-2-Nitrophenyl)-5-Acetamido-2,6-Anhydro-2,3,5,9-Tetradeoxy-9-Thioglycerogalactonon-2-Enonic Acid CAS NO 112848-77-8
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CAS No.:112848-77-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9-S-(4-Azido-2-Nitrophenyl)-5-Acetamido-2,6-Anhydro-2,3,5,9-Tetradeoxy-9-Thioglycerogalactonon-2-Enonic Acid is a specialized, high-purity biochemical building block featuring a reactive azido group. This compound is critical for advanced research and development in bioconjugation and carbohydrate chemistry, enabling the precise modification of biomolecules. It is primarily sought by pharmaceutical R&D teams, diagnostic developers, and academic researchers working on targeted drug delivery systems, novel biosensors, and complex glycoconjugate synthesis.
Application
- Bioconjugation Reagent: Used as a key intermediate for "click chemistry" reactions to attach carbohydrates, peptides, or other functional groups to proteins, antibodies, or nanoparticles.
- Pharmaceutical Research: Serves as a critical building block in the synthesis of targeted therapeutics, including antibody-drug conjugates (ADCs) and glyco-engineered drugs.
- Diagnostic Probe Development: Employed in the creation of fluorescent or affinity-based probes for cellular imaging and biomarker detection.
- Glycobiology Studies: Essential for synthesizing defined oligosaccharide analogs and sialic acid derivatives to study carbohydrate-protein interactions.
- Material Science Functionalization: Used to introduce bio-recognition elements onto surfaces for biosensor and microarray platforms.
- Chemical Biology Tool: Acts as a photoactivatable crosslinker or affinity tag in proteomics and interactome mapping studies.
Basic Information
| Product Name | 9-S-(4-Azido-2-Nitrophenyl)-5-Acetamido-2,6-Anhydro-2,3,5,9-Tetradeoxy-9-Thioglycerogalactonon-2-Enonic Acid |
| CAS No. | 112848-77-8 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | 5-Acetamido-9-S-(4-azido-2-nitrophenyl)-2,6-anhydro-2,3,5,9-tetradeoxy-9-thio-D-glycero-D-galacto-non-2-enonic acid; Sialic Acid Azido Derivative; ANP-Sialic Acid; 9-Thiosialic Acid Azide; Azidoaryl Thiosialoside; Photoreactive Sialic Acid Analog; Bioconjugation Sialic Acid Reagent |
| EINECS | Contact for details |
Quality Control
Our 9-S-(4-Azido-2-Nitrophenyl)-5-Acetamido-2,6-Anhydro-2,3,5,9-Tetradeoxy-9-Thioglycerogalactonon-2-Enonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the exacting standards required for life science research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is both light-sensitive and hygroscopic (moisture-sensitive). For long-term stability, store in a freezer and allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Solubility | Soluble in DMSO, DMF; Slightly soluble in water |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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