Description

Methyllycaconitine Citrate is a high-purity, potent alkaloid compound widely recognized for its selective antagonistic activity at specific nicotinic acetylcholine receptors. This specificity makes it a critical research tool for neuropharmacological studies and drug discovery programs. It is essential for academic, pharmaceutical, and biotechnology laboratories investigating receptor function, signal transduction pathways, and the development of novel therapeutic agents.

Application

• Neuroscience Research: A selective antagonist for α7 and other neuronal nicotinic acetylcholine receptors (nAChRs) used in receptor characterization and binding studies.
• Pharmacological Studies: Employed in vitro and in vivo to investigate cholinergic signaling, cognitive function, and pain pathways.
• Drug Discovery & Development: Serves as a reference standard and pharmacological tool in high-throughput screening (HTS) and lead optimization for neurological disorders.
• Biochemical Assays: Used in the development and validation of assays targeting nAChR activity, including calcium flux and electrophysiology.
• Toxicology Research: Applied in studies examining the mechanisms of action of natural neurotoxins and related synthetic analogs.

Basic Information

Product Name	Methyllycaconitine Citrate
CAS No.	112825-05-5
Molecular Formula	C37H50N2O10 • xC6H8O7
Molecular Weight	Contact for details
Synonyms	MLA Citrate; Methyllycaconitine citrate salt; (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxyaconitane-7,8-diol citrate; 16β-Methyllycaconitine citrate; Lycoctonine, 16-methyl-, citrate
EINECS	Contact for details

Quality Control

Our Methyllycaconitine Citrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.