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Udp-3-O[R-3-Hydroxymyristoyl]-n-Acetylglucosamine Tris Salt CAS NO 112710-84-6
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CAS No.:112710-84-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Udp-3-O[R-3-Hydroxymyristoyl]-n-Acetylglucosamine Tris Salt is a key biochemical intermediate, specifically a lipid-linked precursor in the biosynthesis of bacterial cell wall components. This compound is essential for researchers studying the molecular mechanisms of bacterial peptidoglycan assembly and for screening novel antibacterial agents that target this pathway. It is primarily utilized by pharmaceutical R&D teams, academic biochemistry laboratories, and companies developing enzyme inhibitors for therapeutic applications.
Application
- Biochemical Research: Critical substrate for studying the enzymatic activity of MurG and other transferases in the peptidoglycan biosynthesis pathway.
- Antibacterial Drug Discovery: Used in high-throughput screening assays to identify and characterize novel inhibitors of bacterial cell wall synthesis.
- Enzyme Kinetics & Mechanism Studies: Serves as a precise tool for determining kinetic parameters (Km, Vmax) and elucidating the catalytic mechanisms of glycosyltransferases.
- Metabolic Pathway Analysis: Employed in tracing and quantifying the flux through the lipid cycle II in bacterial systems using analytical techniques like LC-MS.
- Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of bacterial cell wall precursors in quality control and diagnostic applications.
Basic Information
| Product Name | Udp-3-O[R-3-Hydroxymyristoyl]-n-Acetylglucosamine Tris Salt |
| CAS No. | 112710-84-6 |
| Molecular Formula | C37H65N3O19P2 • xC4H11NO3 |
| Molecular Weight | Contact for details |
| Synonyms | UDP-3-O-(R-3-Hydroxymyristoyl)-N-acetylglucosamine Tris Salt; UDP-3-O-(3-Hydroxytetradecanoyl)-N-acetyl-α-D-glucosamine Tris Salt; Lipid I Analog Tris Salt; UDP-MurNAc-pentapeptide precursor; UDP-GlcNAc-(3-O-acyl) Tris Salt; Bacterial Cell Wall Precursor; UDP-3-O-(14:0(3-OH))-GlcNAc Tris Salt; Uridine Diphosphate N-Acetylglucosamine Hydroxymyristoyl Derivative Tris Salt |
| EINECS | Contact for details |
Quality Control
Our Udp-3-O[R-3-Hydroxymyristoyl]-n-Acetylglucosamine Tris Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0 % |
| Solvent Residues (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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