Description

Sucrose-(Fructose-1-3H(N)) is a radiolabeled sucrose derivative, specifically tritiated at the 1-position of the fructose moiety. This compound is a critical tool for metabolic and biochemical research, enabling precise tracking and quantification of sucrose uptake, transport, and metabolism in biological systems. It is essential for researchers and analytical laboratories in the pharmaceutical, agricultural, and food science industries who require high-specific-activity tracers for sensitive in vitro and in vivo studies.

Application

• Metabolic Pathway Tracing: Used as a radiotracer to study sucrose metabolism, catabolism, and anabolic processes in plants, microorganisms, and mammalian systems.
• Membrane Transport Studies: Essential for investigating the kinetics and mechanisms of sucrose transporters (e.g., SUT/SUC family) in plant physiology and gut biology.
• Pharmacokinetics & Drug Delivery Research: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies for drug formulations where sucrose is used as an excipient or stabilizer.
• Enzymology Assays: Serves as a substrate for assays involving enzymes like invertase (sucrase) to measure activity and inhibition.
• Agricultural Science: Applied in research on photosynthesis, carbon partitioning, and sugar translocation in crops to improve yield and stress resistance.
• Food Science & Nutrition: Utilized in studies on dietary sugar digestion, absorption, and their metabolic fate.

Basic Information

Product Name	Sucrose-(Fructose-1-3H(N))
CAS No.	112642-98-5
Molecular Formula	C₁₂H₂₁(³H)NO₁₁ *
Molecular Weight	Contact for details
Synonyms	1-(3)H-Fructosyl-α-D-glucopyranoside
[1-³H]Fructose-Sucrose
Sucrose (fructose-1-tritiated)
Tritiated Sucrose (Fructose-1-³H)
α-D-Glucopyranosyl-1-(3)H-β-D-fructofuranoside
D-(+)-Sucrose (Fructose-1-³H)
³H-Sucrose (specific position)
EINECS	Contact for details

* Formula indicates tritium (³H) substitution at the C-1 position of the fructose unit.

Quality Control

Every batch of our radiolabeled compounds is produced and analyzed under stringent quality protocols. Radiochemical purity and specific activity are determined using validated methods such as HPLC with radiometric detection and liquid scintillation counting (LSC). We provide comprehensive Certificates of Analysis (COA) detailing batch-specific data including purity, concentration, solvent, and analytical chromatograms. Our quality system supports research requiring traceability and compliance with GLP (Good Laboratory Practice) standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at ≤ -20°C or as recommended on the specific COA. The product is supplied in a suitable solvent (e.g., aqueous ethanol). Always handle with appropriate safety measures for radioactive materials in a designated laboratory area. Allow the vial to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Chemical Purity (HPLC)	≥ 95%
Radiochemical Purity	≥ 97%
Specific Activity	10-40 Ci/mmol (Contact for exact value)
Concentration	1 mCi/mL (approx.) in specified solvent
Solvent	Ethanol: Water (9:1 v/v) or as specified
Identification (HPLC)	Co-elutes with authentic standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.