Description

n-(2'-(S)-Hydroxylignoceroyl)-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, a critical building block for advanced biochemical and pharmaceutical research. This compound is essential for studying and modulating cellular signaling pathways, particularly those involving ceramide metabolism and cell membrane dynamics. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical R&D, and advanced cosmetics industries for its role in creating novel therapeutic agents and high-performance biomaterials.

Application

• Biochemical Research: A key precursor for the synthesis of complex sphingolipids and glycosphingolipids used in signal transduction studies.
• Pharmaceutical Development: Serves as an intermediate in the research and production of potential therapeutics targeting cancer, neurodegenerative diseases, and metabolic disorders.
• Lipidomics Standards: Used as a certified reference standard in mass spectrometry for the accurate quantification and profiling of sphingolipids in biological samples.
• Cell Biology Studies: Employed to investigate apoptosis, cell proliferation, and stress responses mediated by the sphingolipid rheostat.
• Cosmeceutical R&D: Explored for its potential in advanced skincare formulations aimed at enhancing skin barrier function and cellular communication.
• Enzyme Substrate: Acts as a specific substrate for enzymes like ceramidases and sphingomyelin synthases in enzymatic assays and inhibitor screening.

Basic Information

Item	Details
Product Name	n-(2'-(S)-Hydroxylignoceroyl)-D-Erythro-Sphingosine
CAS No.	112317-53-0
Molecular Formula	C46H91NO5
Molecular Weight	738.23 g/mol
Synonyms	N-(2-Hydroxytetracosanoyl)-D-erythro-sphingosine; N-(2'-Hydroxylignoceroyl)-D-erythro-sphingosine; C24:0 α-Hydroxy Ceramide (d18:1/24:0h); (2S,3R,4E)-2-[(2R)-2-Hydroxytetracosanoylamino]-4-octadecene-1,3-diol; α-Hydroxy-N-lignoceroylsphingosine; Ceramide NS 24:0; D-erythro-C24 α-Hydroxy Ceramide; Phytosphingosine-based α-hydroxy ceramide
EINECS	Contact for details

Quality Control

Every batch of n-(2'-(S)-Hydroxylignoceroyl)-D-Erythro-Sphingosine is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We ensure high purity and batch-to-batch consistency through advanced techniques like HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Due to its hygroscopic nature, the container must be sealed and stored in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.