Description

16-o-Methyl-14,15-Didehydroisovincal is a high-purity, specialized alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate for the development of novel therapeutic agents and complex natural product analogs. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on oncology, neurology, and other life science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel vinca alkaloid analogs and other complex bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates with targeted mechanisms of action.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating tubulin binding and inhibition, relevant to anticancer research.
• Fine Chemical Synthesis: Utilized as a sophisticated precursor in multi-step organic syntheses for complex natural products.
• Academic Research: A valuable compound for universities and research institutes studying alkaloid chemistry and biosynthesis.

Basic Information

Product Name	16-o-Methyl-14,15-Didehydroisovincal
CAS No.	112237-71-5
Molecular Formula	C22H24N2O2
Molecular Weight	348.44 g/mol
Synonyms	16-O-Methyl-14,15-didehydroisovincaleukoblastine; 16-OMe-14,15-didehydroisovincaleukoblastine; Isovincaleukoblastine, 16-O-methyl-14,15-didehydro-; 16-O-Methyl-14,15-didehydroisovincaleukoblastin; 16-O-Methyl-14,15-didehydroisovincaleucoblastine; 16-O-Methyl-14,15-anhydroisovincaleukoblastine; 16-Methoxy-14,15-didehydroisovincaleukoblastine
EINECS	Contact for details

Quality Control

Our 16-o-Methyl-14,15-Didehydroisovincal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.