Description

14,15-Didehydrovincamenine is a specialized indole alkaloid derivative, recognized for its unique structural framework and potential as a key intermediate in advanced organic synthesis. This compound is valued for its role in the research and development of novel pharmaceutical agents and bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, neuroscience studies, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Research Intermediate: A critical building block in the synthesis of novel vinca alkaloid derivatives and other complex indole-based therapeutic candidates.
• Medicinal Chemistry Studies: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles for central nervous system (CNS) targets.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Natural Product Synthesis: Employed in the semi-synthesis and total synthesis of complex natural products for academic and industrial research.
• Biochemical Research: Utilized in in-vitro studies to investigate interactions with biological receptors and enzymes.

Basic Information

Product Name	14,15-Didehydrovincamenine
CAS No.	112219-48-4
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Vincamenine, 14,15-didehydro-; 14,15-Dehydrovincamenine; (19S)-19-Ethyl-1,11-diazapentacyclo[9.6.2.0¹,⁸.0²,⁷.0¹⁵,¹⁸]nonadeca-2,4,6,8,15-pentaene-9,20-dione; Vincaminorine; Apovincaminic acid ethyl ester derivative
EINECS	Contact for details

Quality Control

Our 14,15-Didehydrovincamenine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support research and development with material that meets stringent in-house specifications, suitable for use as a reference standard or advanced synthetic intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.