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D-Glucosyl--1,1' n-Lauroyl-D-Erythro-Sphingosine CAS NO 111956-48-0


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CAS No.:111956-48-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Glucosyl-β-1,1' n-Lauroyl-D-Erythro-Sphingosine is a synthetic, high-purity glycosphingolipid derivative, specifically a glucosylceramide with a lauroyl fatty acid chain. This compound is a critical biochemical tool and advanced intermediate for research and development in lipidomics and cell biology. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries for studying cell membrane structure, signal transduction pathways, and developing novel therapeutic and skincare agents.

Application

  • Biochemical Research: As a standard or substrate for studying glycosphingolipid metabolism, enzyme kinetics (e.g., glucocerebrosidase activity), and lipid raft formation.
  • Pharmaceutical Development: An important intermediate in the synthesis of more complex sphingolipids for investigating targets in metabolic disorders, oncology, and neurodegenerative diseases.
  • Cosmetic Science: Used in advanced skincare formulations for research into ceramide analogs that support skin barrier function and hydration.
  • Cell Biology Studies: Incorporation into model membranes (liposomes, bilayers) to investigate cell signaling, apoptosis, and receptor function.
  • Diagnostic Reagent Production: Potential use as a key component in enzymatic assay kits for diagnosing lysosomal storage disorders like Gaucher disease.
  • Academic Research: A vital reagent for universities and research institutes focusing on glycobiology and sphingolipid-mediated processes.

Basic Information

Product Name D-Glucosyl-β-1,1' n-Lauroyl-D-Erythro-Sphingosine
CAS No. 111956-48-0
Molecular Formula C40H75NO9
Molecular Weight 714.03 g/mol
Synonyms N-Lauroyl-D-erythro-sphingosyl-β-D-glucoside; β-D-Glucosyl-N-lauroyl-D-erythro-sphingosine; Lauroyl Glucosylceramide; N-Lauroyl-Glucosylceramide; D-Glucosyl-β-1,1' N-Lauroyl-D-erythro-sphingosine; GlcCer(d18:1/12:0); N-(Dodecanoyl)-1-β-D-glucopyranosyl-sphing-4-enine; Glucosylceramide (d18:1/12:0)
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Quality Control

Our D-Glucosyl-β-1,1' n-Lauroyl-D-Erythro-Sphingosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and analytical methods are provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC/MS) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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