Description

Coenzyme A Acetyl Derivative, Disodium Salt is a high-purity biochemical reagent essential for metabolic research and enzymatic synthesis. This compound serves as a critical acetyl group donor and cofactor in key biochemical pathways, including the citric acid cycle and fatty acid metabolism. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers for applications in enzymology, metabolic studies, and high-value biosynthetic processes.

Application

• Biochemical Research & Enzymology: Used as a substrate or cofactor in enzymatic assays to study acetyltransferase activity, metabolic flux, and energy production pathways.
• Pharmaceutical Development: Employed in the research and synthesis of novel drug candidates targeting metabolic disorders and enzyme-related diseases.
• Diagnostic Reagent Manufacturing: A key component in the formulation of clinical diagnostic kits for measuring specific enzyme activities in blood and tissue samples.
• Metabolomics & Systems Biology: Serves as a standard or reagent in mass spectrometry and chromatography-based studies to map and quantify metabolic networks.
• Academic & Industrial R&D: Fundamental for basic research in biochemistry, molecular biology, and cellular physiology within university and corporate laboratories.

Basic Information

Product Name	Coenzyme A Acetyl Derivative, Disodium Salt
CAS No.	110972-33-3
Molecular Formula	C23H36N7O17P3S · 2Na
Molecular Weight	~ 809.5 g/mol (Disodium Salt)
Synonyms	Acetyl Coenzyme A, Disodium Salt; Acetyl-CoA, Disodium Salt; S-Acetyl Coenzyme A, Disodium Salt; AcCoA-Na2; CoA S-Acetate, Disodium Salt; Acetyl-Coenzyme A Sodium Salt; 3'-dephospho-CoA S-acetate, Disodium Salt
EINECS	Contact for details

Quality Control

Our Coenzyme A Acetyl Derivative, Disodium Salt is manufactured under strict quality controls to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not intended for human therapeutic use, our production adheres to principles of Good Manufacturing Practice (GMP) for fine chemicals, ensuring reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For extended storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95% (on anhydrous basis)
Purity (HPLC)	≥ 98.0% (Total peak area)
Water Content (KF)	≤ 5.0 %
pH (in solution)	6.0 - 8.0
Biological Activity	Conforms (Enzymatic assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.