Description

S-3'-Deoxy-7-Deazaadenosylhomocysteine is a chemically modified nucleoside analog of S-adenosylhomocysteine (SAH). This compound matters as a potent and selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH), playing a critical role in regulating cellular methylation processes. It is primarily needed by researchers and developers in the fields of epigenetics, antiviral drug discovery, and biochemical research, where precise modulation of methylation pathways is essential.

Application

• Biochemical Research: As a key tool compound for studying methylation-dependent pathways and enzyme mechanisms.
• Antiviral Development: Investigation as a potential lead compound for antiviral therapies targeting viruses dependent on host methylation.
• Epigenetics Studies: Used to inhibit SAHH and modulate intracellular levels of SAH, thereby influencing DNA and histone methylation patterns.
• Enzyme Inhibition Assays: Serves as a standard inhibitor in high-throughput screening and kinetic studies of SAHH activity.
• Pharmaceutical Intermediates: Potential use as a sophisticated building block in the synthesis of novel nucleoside-based therapeutics.
• Academic Research: Fundamental research in molecular biology and cellular signaling where methylation is a regulatory component.

Basic Information

Product Name	S-3'-Deoxy-7-Deazaadenosylhomocysteine
CAS No.	110880-46-1
Molecular Formula	C15H20N6O4S
Molecular Weight	380.42 g/mol
Synonyms	7-Deaza-S-tubercidinylhomocysteine; 3'-Deoxy-S-tubercidinylhomocysteine; 7-Carba-S-tubercidinylhomocysteine; S-(3-Deoxy-7-deazaadenosyl)homocysteine; 7-Deaza-aristeromycinylhomocysteine; SAH Hydrolase Inhibitor (7-deaza analog); 3'-Deoxy-7-deaza-S-adenosylhomocysteine
EINECS	Contact for details

Quality Control

Our S-3'-Deoxy-7-Deazaadenosylhomocysteine is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.