Description

1-o-Hexadecyl-2-Acetyl-3-Thiophosphocholine is a synthetic, high-purity phospholipid analog with a unique thiophosphocholine head group. This compound is valued for its role as a key intermediate and research chemical in advanced lipid-based formulations. It is primarily required by researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel drug delivery systems and studying membrane biochemistry.

Application

• Pharmaceutical Research: As a critical intermediate in the synthesis of novel phospholipid-based drug delivery vehicles, such as liposomes and lipid nanoparticles (LNPs).
• Biochemical Studies: Used as a specialized substrate or analog in enzymatic studies related to phospholipid metabolism and cell signaling pathways.
• Advanced Material Science: A building block for creating functionalized lipid membranes and surfaces with tailored properties for biosensors or diagnostic devices.
• Cosmetic & Dermal Formulations: Potential use as a high-performance ingredient in advanced cosmetic products requiring enhanced skin barrier function and delivery.

Basic Information

Product Name	1-o-Hexadecyl-2-Acetyl-3-Thiophosphocholine
CAS No.	110786-03-3
Molecular Formula	C23H49NO4PS
Molecular Weight	466.67 g/mol
Synonyms	1-Hexadecyl-2-acetyl-sn-glycero-3-thiophosphocholine; 1-O-Hexadecyl-2-acetyl-3-thiophosphocholine; 1-O-Hexadecyl-2-acetyl-sn-glycero-3-thiophosphocholine; 2-Acetyl-1-O-hexadecyl-3-thiophosphocholine; 1-Hexadecyl-2-acetyl-glycero-3-thiophosphocholine; 1-O-Hexadecyl-2-acetyl-glycero-3-thiophosphocholine; PAF Analog Thiophosphocholine Derivative; 1-Alkyl-2-acetyl-sn-glycero-3-thiophosphocholine (C16:0)
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Acetyl-3-Thiophosphocholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.