Description

n-(10-(1-Pyrenyl)Decanoyl)Glucocerebroside is a synthetic, fluorescently labeled derivative of glucocerebroside, a key sphingolipid. This compound is engineered for high-performance research, offering a powerful tool for the study of lipid metabolism, membrane dynamics, and intracellular trafficking. It is primarily utilized by researchers and scientists in the fields of biochemistry, cell biology, and pharmacology for advanced analytical and diagnostic applications.

Application

• Biochemical Research: As a fluorescent probe for studying glucocerebroside metabolism, lysosomal storage disorders (e.g., Gaucher disease), and sphingolipid biology.
• Cell Biology Studies: For tracing lipid transport, membrane fusion processes, and organelle dynamics within living cells using fluorescence microscopy.
• Diagnostic Assay Development: Serving as a critical substrate or standard in the development of enzymatic assays for diagnosing lysosomal enzyme deficiencies.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and evaluate potential therapeutic compounds that modulate glucocerebrosidase activity.
• Lipidomics and Analytical Standards: Acting as a reference standard in mass spectrometry and chromatography for the precise quantification of glucocerebroside and related metabolites.

Basic Information

Product Name	n-(10-(1-Pyrenyl)Decanoyl)Glucocerebroside
CAS No.	110668-37-6
Molecular Formula	C52H81NO11
Molecular Weight	896.20 g/mol
Synonyms	Pyrene-labeled Glucocerebroside; 1-O-[N-(10-(1-Pyrenyl)decanoyl)]-β-D-glucosylsphingosine; N-(10-(1-Pyrenyl)decanoyl)-D-glucosyl-β1-1'-sphingosine; Fluorescent Glucocerebroside; Pyrene-C10-Glucocerebroside; Glucocerebroside, N-(10-(1-pyrenyl)decanoyl)-; Glucosylceramide, N-(10-(1-pyrenyl)decanoyl)-
EINECS	Contact for details

Quality Control

Our n-(10-(1-Pyrenyl)Decanoyl)Glucocerebroside is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and fluorescence spectroscopy to ensure optimal performance. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is both light-sensitive and hygroscopic. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store in aliquots under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Fluorescence Properties	Excitation/Emission maxima typical for pyrene label
Solubility	Soluble in chloroform, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.