Description

Leucinostatin C CAS NO 110483-88-0 is a potent, non-ribosomal peptide antibiotic belonging to the leucinostatin family, characterized by its complex cyclic depsipeptide structure. This compound is valued for its significant biological activity, particularly as a strong antifungal and antitumor agent, making it a critical tool in biochemical and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies investigating novel therapeutic pathways and antimicrobial mechanisms.

Application

• Biochemical Research: Serves as a reference standard and active agent in studies of mitochondrial function, ATPase inhibition, and ionophore activity.
• Antifungal Agent Development: Investigated for its potent activity against a broad spectrum of pathogenic fungi, including strains resistant to conventional therapies.
• Antitumor and Cytotoxicity Studies: Used in oncology research to study its effects on apoptosis and cell proliferation in various cancer cell lines.
• Mode of Action Studies: Employed to elucidate the mechanisms of non-ribosomal peptide synthesis and membrane-disrupting antibiotic activity.
• Pharmaceutical R&D: Acts as a lead compound or molecular scaffold in the discovery and development of new antimicrobial and chemotherapeutic agents.

Basic Information

Product Name	Leucinostatin C
CAS No.	110483-88-0
Molecular Formula	C₆₃H₁₁₃N₁₁O₁₃
Molecular Weight	1240.6 g/mol
Synonyms	Leucinostatin C; Antibiotic PF 1018; Leucinostatin C (Antibiotic PF 1018); Leucinostatin C, PF 1018; PF-1018; PF1018; Leucinostatin C from Paecilomyces lilacinus; UNII-2Z5V9N1A1G
EINECS	Contact for details

Quality Control

Our Leucinostatin C is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals, ensuring reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.